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1LY4:
Analysis of quinazoline and PYRIDO[2,3D]PYRIMIDINE N9-C10 reversed bridge antifolates in complex with NADP+ and Pneumocystis carinii dihydrofolate reductase
PDB ID:
1LY4
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MMDB ID:
20483
PDB Deposition Date:
2002/6/6
Updated in MMDB:
2007/10
Experimental Method:
x-ray diffraction
Resolution:
2.1 Å
Source Organism:
Pneumocystis carinii
Similar Structures:
VAST+
Download sequence data
Biological Unit for 1LY4: monomeric; determined by author
Molecular Components in 1LY4
Label
Count
Molecule
Protein (1 molecule)
A
1
Dihydrofolate Reductase
Chemicals and Non-standard biopolymers (2 molecules)
1
1
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
1
2,4-DIAMINO-6-[N-(3',5'-DIMETHOXYBENZYL)-N-METHYLAMINO]PYRIDO[2,3-D]PYRIMIDINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303